Melinda M. Mulvihill, Ph.D.

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics
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"Melinda Mulvihill"
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Parents

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Elizabeth A. Komives grad student 2011 UCSD
 (Post-translational modifications in intrinsically disordered regions and their contribution to protein-protein interactions.)
Daniel K. Nomura post-doc UC Berkeley
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Publications

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Kohnz RA, Mulvihill MM, Chang JW, et al. (2015) Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. Acs Chemical Biology. 10: 1624-30
Rashidian J, Le Scolan E, Ji X, et al. (2015) Ski regulates Hippo and TAZ signaling to suppress breast cancer progression. Science Signaling. 8: ra14
Chang JW, Zuhl AM, Speers AE, et al. (2015) Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. Acs Chemical Biology. 10: 925-32
Mulvihill MM, Benjamin DI, Ji X, et al. (2014) Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity. Chemistry & Biology. 21: 831-40
Mulvihill MM, Nomura DK. (2014) Metabolomic strategies to map functions of metabolic pathways. American Journal of Physiology. Endocrinology and Metabolism. 307: E237-44
Benjamin DI, Louie SM, Mulvihill MM, et al. (2014) Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness. Acs Chemical Biology. 9: 1340-50
Morris PJ, Medina-Cleghorn D, Heslin A, et al. (2014) Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia. Acs Chemical Biology. 9: 1097-103
Medina-Cleghorn D, Heslin A, Morris PJ, et al. (2014) Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides. Acs Chemical Biology. 9: 423-32
Benjamin DI, Cozzo A, Ji X, et al. (2013) Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity. Proceedings of the National Academy of Sciences of the United States of America. 110: 14912-7
Louie SM, Roberts LS, Mulvihill MM, et al. (2013) Cancer cells incorporate and remodel exogenous palmitate into structural and oncogenic signaling lipids. Biochimica Et Biophysica Acta. 1831: 1566-72
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