Cecilia Y. Cheng, Ph.D.
Affiliations: | 2009 | Chemistry | University of California, San Diego, La Jolla, CA |
Area:
Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase SuperfamilyGoogle:
"Cecilia Cheng"Mean distance: 9.74 | S | N | B | C | P |
Parents
Sign in to add mentor| Susan Serota Taylor | grad student | 2009 | UCSD | |
| (Dissecting the allosteric regulation of PKA-I alpha activation.) | ||||
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Publications
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| Lu TW, Wu J, Aoto PC, et al. (2019) Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proceedings of the National Academy of Sciences of the United States of America |
| Brown SH, Cheng CY, Saldanha SA, et al. (2013) Implementing fluorescence anisotropy screening and crystallographic analysis to define PKA isoform-selective activation by cAMP analogs. Acs Chemical Biology. 8: 2164-72 |
| Lie PP, Mruk DD, Mok KW, et al. (2012) Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat. Proceedings of the National Academy of Sciences of the United States of America. 109: 12562-7 |
| Masterson LR, Cheng C, Yu T, et al. (2011) Erratum: Corrigendum: Dynamics connect substrate recognition to catalysis in protein kinase A Nature Chemical Biology. 7: 319-319 |
| Masterson LR, Cheng C, Yu T, et al. (2010) Dynamics connect substrate recognition to catalysis in protein kinase A. Nature Chemical Biology. 6: 821-8 |
| Cheng CY, Yang J, Taylor SS, et al. (2009) Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering. The Journal of Biological Chemistry. 284: 35916-25 |
| Taylor SS, Kim C, Cheng CY, et al. (2008) Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. Biochimica Et Biophysica Acta. 1784: 16-26 |
| Kim C, Cheng CY, Saldanha SA, et al. (2007) PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell. 130: 1032-43 |
| Taylor SS, Kim CW, Cheng CY, et al. (2002) Fifty Years Since the Discovery of PKA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4123 |