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Jon M. Steichen, Ph.D.

Affiliations: 
2012 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily
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"Jon Steichen"
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Susan Serota Taylor grad student 2012 UCSD
 (Investigating the Role of Turn Motif and Activation Loop Phosphorylation in the Regulation of PKA Structure and Function.)

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Publications

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Taylor SS, Zhang P, Steichen JM, et al. (2013) PKA: lessons learned after twenty years. Biochimica Et Biophysica Acta. 1834: 1271-8
Bastidas AC, Deal MS, Steichen JM, et al. (2013) Phosphoryl transfer by protein kinase A is captured in a crystal lattice. Journal of the American Chemical Society. 135: 4788-98
Taylor SS, Keshwani MM, Steichen JM, et al. (2012) Evolution of the eukaryotic protein kinases as dynamic molecular switches. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2517-28
Bastidas AC, Deal MS, Steichen JM, et al. (2012) Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. Journal of Molecular Biology. 422: 215-29
Steichen JM, Kuchinskas M, Keshwani MM, et al. (2012) Structural basis for the regulation of protein kinase A by activation loop phosphorylation. The Journal of Biological Chemistry. 287: 14672-80
Yang J, Wu J, Steichen JM, et al. (2012) A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. Journal of Molecular Biology. 415: 666-79
Steichen JM, Iyer GH, Li S, et al. (2010) Global consequences of activation loop phosphorylation on protein kinase A. The Journal of Biological Chemistry. 285: 3825-32
Steichen JM, Petty RV, Sharkey TD. (2008) Domain characterization of a 4-alpha-glucanotransferase essential for maltose metabolism in photosynthetic leaves. The Journal of Biological Chemistry. 283: 20797-804
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