Brian R. Blank, Ph.D.

Affiliations: 
2014 Chemistry 0153 University of California, Los Angeles, Los Angeles, CA 
Area:
Synthetic Methods, Target-Oriented Synthesis, Chemical Diversity
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Ohyun Kwon grad student 2014 UCLA
 (Synthetic Studies Toward the Total Synthesis of (+/-)-Ajmaline and the Development of, Investigation into, and Application of a Phosphine-Catalyzed [4+1] Annulation.)
Adam R. Renslo post-doc 2014-2017 UCSF
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Publications

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Blank BR, Gut J, Rosenthal PJ, et al. (2023) Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. Acs Medicinal Chemistry Letters. 14: 493-498
Blank BR, Andrews IP, Kwon O. (2020) Phosphine-Catalyzed (4+1) Annulation: Rearrangement of Allenylic Carbamates to 3-Pyrrolines through Phosphonium Diene Intermediates. Chemcatchem. 12: 4352-4372
Blank B, Gonciarz R, Talukder P, et al. (2020) Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy. Acs Infectious Diseases
Blank BR, Andrews IP, Kwon O. (2020) Phosphine‐Catalyzed (4+1) Annulation: Rearrangement of Allenylic Carbamates to 3‐Pyrrolines through Phosphonium Diene Intermediates Chemcatchem. 12: 4352-4372
Blank B, Talukder P, Muir R, et al. (2019) Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor. Acs Infectious Diseases
Aron AT, Heffern MC, Lonergan ZR, et al. (2017) In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection. Proceedings of the National Academy of Sciences of the United States of America
Blank BR, Gut J, Rosenthal PJ, et al. (2017) Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. Journal of Medicinal Chemistry
Andrews IP, Blank BR, Kwon O. (2012) Phosphine-catalyzed intramolecular γ-umpolung addition of α-aminoalkylallenic esters: facile synthesis of 3-carbethoxy-2-alkyl-3-pyrrolines. Chemical Communications (Cambridge, England). 48: 5373-5
Andrews IP, Blank BR, Kwon O. (2012) ChemInform Abstract: Phosphine-Catalyzed Intramolecular γ-Umpolung Addition of α-Aminoalkylallenic Esters: Facile Synthesis of 3-Carbethoxy-2-alkyl-3-pyrrolines. Cheminform. 43: no-no
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