Jeremiah J. Frye, Ph.D.
Affiliations: | 2010 | University of Wisconsin, Madison, Madison, WI |
Area:
Structural BiologyGoogle:
"Jeremiah Frye"Mean distance: 9.4 | S | N | B | C | P |
Parents
Sign in to add mentor| Ivan Rayment | grad student | 2010 | UW Madison | |
| (Novel approaches to stabilizing and crystallizing coiled-coil containing proteins.) | ||||
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Publications
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| Chari A, Haselbach D, Kirves JM, et al. (2015) ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods. 12: 859-65 |
| Brown NG, VanderLinden R, Watson ER, et al. (2015) RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex. Proceedings of the National Academy of Sciences of the United States of America. 112: 5272-9 |
| Yamaguchi M, Yu S, Qiao R, et al. (2015) Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. Journal of Molecular Biology. 427: 1748-64 |
| Brown NG, Watson ER, Weissmann F, et al. (2014) Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly. Molecular Cell. 56: 246-60 |
| Frye JJ, Brown NG, Petzold G, et al. (2013) Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown. Nature Structural & Molecular Biology. 20: 827-35 |
| Klenchin VA, Frye JJ, Jones MH, et al. (2011) Structure-function analysis of the C-terminal domain of CNM67, a core component of the Saccharomyces cerevisiae spindle pole body. The Journal of Biological Chemistry. 286: 18240-50 |
| Frye J, Klenchin VA, Rayment I. (2010) Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition. Biochemistry. 49: 4908-20 |
| Frye JJ, Klenchin VA, Bagshaw CR, et al. (2010) Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236. Biochemistry. 49: 4897-907 |