Sarah M. McWhirter, Ph.D.

Affiliations: 
2000 University of California, Berkeley, Berkeley, CA, United States 
Area:
host-pathogen interactions, motions in proteins
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"Sarah McWhirter"
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Thomas C. Alber grad student 2000 UC Berkeley
 (Crystallographic analysis of tumor necrosis factor receptor-associated factor 2 (TRAF2).)
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Publications

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Nicolai CJ, Wolf N, Chang IC, et al. (2020) NK cells mediate clearance of CD8 T cell-resistant tumors in response to STING agonists. Science Immunology. 5
Deng W, Desbien AL, Gauthier KS, et al. (2020) Abstract PR09: ADU-S100 (MIW815) synergizes with checkpoint blockade to elicit an antitumor CD8+ T-cell response to control distal tumors Cancer Immunology Research. 8
Sivick KE, Desbien AL, Glickman LH, et al. (2019) Magnitude of Therapeutic STING Activation Determines CD8 T Cell-Mediated Anti-tumor Immunity. Cell Reports. 29: 785-789
Luteijn RD, Zaver SA, Gowen BG, et al. (2019) SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 573: 434-438
Corrales L, Desbien AL, Gauthier KES, et al. (2019) Abstract 1202: Tumor cell intrinsic STING signaling demonstrates minimal contribution to the anti-tumor response elicited by the STING agonist ADU-S100 (MIW815) Cancer Research. 79: 1202-1202
Sivick KE, Desbien AL, Glickman LH, et al. (2018) Magnitude of Therapeutic STING Activation Determines CD8 T Cell-Mediated Anti-tumor Immunity. Cell Reports. 25: 3074-3085.e5
Desbien AL, Gauthier KS, Corrales L, et al. (2018) Abstract 631: Intratumoral activation of STING with a synthetic cyclic dinucleotide elicits antitumor CD8 T-cell immunity that effectively combines with checkpoint inhibitors Cancer Research. 78: 631-631
Hendriks M, Kreijtz J, Vink P, et al. (2018) Abstract 1702: Assessment of pharmacology and toxicology of anti-CTLA-4 antibody (ADU-1604) in non-human primates and evaluation of local anti-CTLA-4 application Cancer Research. 78: 1702-1702
Sivick KE, Surh NH, Desbien AL, et al. (2017) Comment on "The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele". Journal of Immunology (Baltimore, Md. : 1950). 198: 4183-4185
Corrales L, McWhirter SM, Dubensky TW, et al. (2016) The host STING pathway at the interface of cancer and immunity. The Journal of Clinical Investigation. 126: 2404-2411
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