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James M. Holton, Ph.D.

Affiliations: 
2001 University of California, Berkeley, Berkeley, CA, United States 
Area:
host-pathogen interactions, motions in proteins
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"James Holton"
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Thomas C. Alber grad student 2001 UC Berkeley
 (Elves: Accelerating crystallography.)

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Wolff AM, Nango E, Young ID, et al. (2023) Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nature Chemistry
Madani A, Krause B, Greene ER, et al. (2023) Large language models generate functional protein sequences across diverse families. Nature Biotechnology
Correy GJ, Kneller DW, Phillips G, et al. (2022) The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Science Advances. 8: eabo5083
Correy GJ, Kneller DW, Phillips G, et al. (2022) The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature. Biorxiv : the Preprint Server For Biology
Schuller M, Correy GJ, Gahbauer S, et al. (2021) Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Science Advances. 7
Schuller M, Correy GJ, Gahbauer S, et al. (2020) Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking. Biorxiv : the Preprint Server For Biology
de la Mora E, Coquelle N, Bury CS, et al. (2020) Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures. Proceedings of the National Academy of Sciences of the United States of America
Bruning JM, Wang Y, Oltrabella F, et al. (2019) Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chemical Biology
Holton JM. (2019) Challenge data set for macromolecular multi-microcrystallography. Acta Crystallographica. Section D, Structural Biology. 75: 113-122
Knott GJ, East-Seletsky A, Cofsky JC, et al. (2017) Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nature Structural & Molecular Biology
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