Andrew P. VanDemark, Ph.D.

2002 Johns Hopkins University, Baltimore, MD 
lysine ubiquitination and acetylation, using x-ray crystallography, together with biochemical, biophysical and genetic analysis
"Andrew VanDemark"
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Cynthia Wolberger grad student 2002 Johns Hopkins
 (Structural and biochemical studies of the Mms2 /Ubc13 ubiquitin conjugating enzyme complex from yeast.)
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VanDemark AP, Hrizo SL, Eicher SL, et al. (2022) Itavastatin and Resveratrol increase triosephosphate isomerase protein (TPI) in a newly identified variant, TPIQ181P, that confers TPI deficiency. Disease Models & Mechanisms
Googins MR, Woghiren-Afegbua AO, Calderon M, et al. (2020) Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Rosenbaum JC, Bonilla B, Hengel SR, et al. (2019) The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature Communications. 10: 3515
Roland BP, Richards KR, Hrizo SL, et al. (2019) Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. Biochimica Et Biophysica Acta. Molecular Basis of Disease
Mikulska-Ruminska K, Shrivastava IH, Krieger J, et al. (2019) Characterization of differential dynamics, specificity, and allostery of lipoxygenase family members. Journal of Chemical Information and Modeling
Anthonymuthu TS, Kenny EM, Shrivastava IH, et al. (2018) Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Journal of the American Chemical Society
Wenzel SE, Tyurina YY, Zhao J, et al. (2017) PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. Cell. 171: 628-641.e26
Zalewski JK, Heber S, Mo JH, et al. (2017) Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins. Journal of Visualized Experiments : Jove
Van Oss SB, Shirra MK, Bataille AR, et al. (2016) The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. Molecular Cell
Zalewski JK, Mo JH, Heber S, et al. (2016) Structure of the Shroom-Rho kinase complex reveals a binding interface with monomeric Shroom that regulates cell morphology and stimulates kinase activity. The Journal of Biological Chemistry
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