David D. Shultis, Ph.D.

Affiliations: 
2008 University of Virginia, Charlottesville, VA 
Area:
Structural biology of membrane proteins
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"David Shultis"
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Michael C. Wiener grad student 2008 UVA
 (TonB dependent transport.)
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Publications

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Loll PJ, Grasty KC, Shultis DD, et al. (2024) Discovery and structural characterization of the D-box, a conserved TonB motif that couples an inner-membrane motor to outer-membrane transport. The Journal of Biological Chemistry. 105723
Shultis D, Mitra P, Huang X, et al. (2019) Changing the Apoptosis Pathway through Evolutionary Protein Design. Journal of Molecular Biology
Brender JR, Shultis D, Khattak NA, et al. (2017) An Evolution-Based Approach to De Novo Protein Design. Methods in Molecular Biology (Clifton, N.J.). 1529: 243-264
Shultis D, Dodge G, Zhang Y. (2015) Crystal structure of designed PX domain from cytokine-independent survival kinase and implications on evolution-based protein engineering. Journal of Structural Biology
Mitra P, Shultis D, Brender JR, et al. (2013) An evolution-based approach to De Novo protein design and case study on Mycobacterium tuberculosis. Plos Computational Biology. 9: e1003298
Mitra P, Shultis D, Zhang Y. (2013) EvoDesign: De novo protein design based on structural and evolutionary profiles. Nucleic Acids Research. 41: W273-280
Cierpicki T, Risner LE, Grembecka J, et al. (2010) Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nature Structural & Molecular Biology. 17: 62-8
Shultis DD, Purdy MD, Banchs CN, et al. (2006) Crystallization and preliminary X-ray crystallographic analysis of the Escherichia coli outer membrane cobalamin transporter BtuB in complex with the carboxy-terminal domain of TonB. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 638-41
Shultis DD, Purdy MD, Banchs CN, et al. (2006) Outer membrane active transport: structure of the BtuB:TonB complex. Science (New York, N.Y.). 312: 1396-9
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