Shawn A. Motyka, Ph.D.

2006 Johns Hopkins University, Baltimore, MD 
Biochemistry and molecular biology of parasitic protozoa
"Shawn Motyka"
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Paul T. Englund grad student 2006 Johns Hopkins
 (An RNAi library for identifying mitochondrial DNA replication proteins in Trypanosoma brucei.)
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Li Z, Lindsay ME, Motyka SA, et al. (2008) Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication. Plos Pathogens. 4: e1000048
Milman N, Motyka SA, Englund PT, et al. (2007) Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes. Proceedings of the National Academy of Sciences of the United States of America. 104: 19250-5
Motyka SA, Drew ME, Yildirir G, et al. (2006) Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei. The Journal of Biological Chemistry. 281: 18499-506
Englund PT, Agbo EE, Lindsay ME, et al. (2005) RNAi libraries and kinetoplast DNA. Biochemical Society Transactions. 33: 1409-12
Liu Y, Motyka SA, Englund PT. (2005) Effects of RNA interference of Trypanosoma brucei structure-specific endonuclease-I on kinetoplast DNA replication. The Journal of Biological Chemistry. 280: 35513-20
Liu B, Liu Y, Motyka SA, et al. (2005) Fellowship of the rings: the replication of kinetoplast DNA. Trends in Parasitology. 21: 363-9
Drew ME, Motyka SA, Morris JC, et al. (2005) Inducible RNAi as a forward genetic tool in Trypanosoma brucei Rna Interference Technology: From Basic Science to Drug Development. 247-256
Motyka SA, Englund PT. (2004) RNA interference for analysis of gene function in trypanosomatids. Current Opinion in Microbiology. 7: 362-8
Motyka SA, Zhao Z, Gull K, et al. (2004) Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome. Molecular and Biochemical Parasitology. 134: 163-7
Klingbeil MM, Motyka SA, Englund PT. (2002) Multiple mitochondrial DNA polymerases in Trypanosoma brucei. Molecular Cell. 10: 175-86
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