Laura M. Wingler, Ph.D.
Affiliations: | 2011 | Chemistry | Columbia University, New York, NY |
Area:
Chemical Complementation, Ribosome Chemistry, In Vivo ImagingGoogle:
"Laura Wingler"Mean distance: 8.56 | S | N | B | C | P |
Parents
Sign in to add mentor| Virginia W. Cornish | grad student | 2011 | Columbia | |
| (Harnessing Saccharomyces cerevisiae Genetics for Cell Engineering.) | ||||
| Robert J. Lefkowitz | post-doc | Duke | ||
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Publications
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| Braga Emidio N, Small BM, Keller AR, et al. (2023) Nanobody-mediated dualsteric engagement of the angiotensin receptor broadens biased ligand pharmacology. Molecular Pharmacology |
| Skiba MA, Sterling SM, Rawson S, et al. (2023) Antibodies Expand the Scope of Angiotensin Receptor Pharmacology. Biorxiv : the Preprint Server For Biology |
| Wingler LM, Feld AP. (2021) Nanobodies as probes and modulators of cardiovascular GPCRs. Journal of Cardiovascular Pharmacology |
| McMahon C, Staus DP, Wingler LM, et al. (2020) Synthetic nanobodies as angiotensin receptor blockers. Proceedings of the National Academy of Sciences of the United States of America |
| Wingler LM, Lefkowitz RJ. (2020) Conformational Basis of G Protein-Coupled Receptor Signaling Versatility. Trends in Cell Biology |
| Manglik A, Wingler LM, Rockman HA, et al. (2020) β-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19. Circulation |
| Wingler LM, Skiba MA, McMahon C, et al. (2020) Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR. Science (New York, N.Y.). 367: 888-892 |
| Suomivuori CM, Latorraca NR, Wingler LM, et al. (2020) Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor. Science (New York, N.Y.). 367: 881-887 |
| Staus DP, Hu H, Robertson MJ, et al. (2020) Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc. Nature |
| McMahon C, Wingler L, Staus D, et al. (2020) So Long Llamas: Structure of Activated Angiotensin Receptor Stabilized by a Synthetic Nanobody The Faseb Journal. 34: 1-1 |