Mark L. McLaughlin, Ph.D.

1986-2002 Chemistry Louisiana State University, Baton Rouge, LA, United States 
 2002-2016 Chemistry University of South Florida, Tampa, FL, United States 
Medicinal chemistry, oncology
"Mark McLaughlin"
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Jain P, Badger DB, Liang Y, et al. (2020) Bioactivity improvement via display of the hydrophobic core of HYD1 in a cyclic β-hairpin-like scaffold, MTI-101. Peptide Science (Hoboken, N.J.). 113: e24199
Barber C, Antonucci V, Baumann JC, et al. (2017) A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies. Regulatory Toxicology and Pharmacology : Rtp
Gebhard AW, Jain P, Nair RR, et al. (2013) MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. Molecular Cancer Therapeutics. 12: 2446-58
Drake BL, Morris JL, McLaughlin ML, et al. (2012) Tetra-methyl anthracene-2,3,6,7-tetra-carboxyl-ate-tetra-methyl 9,10-dihydro-9,10-dioxoanthracene-2,3,6,7-tetra-carboxyl-ate (1/1). Acta Crystallographica. Section E, Structure Reports Online. 68: o2540-1
Phelan WA, Ngu-Schwemlein M, Fronczek FR, et al. (2011) 1,2-Dihydro-9H-carbazole-4(3H)-thione. Acta Crystallographica. Section E, Structure Reports Online. 67: o757
Fronczek CF, Kil H, McLaughlin ML, et al. (2010) (S)-(Z)-Methyl 2-[2,3-bis-(benzyl-oxy-carbon-yl)guanidino]-4-methyl-penta-no-ate. Acta Crystallographica. Section E, Structure Reports Online. 67: o27-8
Anderson L, Zhou M, Sharma V, et al. (2010) Facile iterative synthesis of 2,5-terpyrimidinylenes as nonpeptidic alpha-helical mimics. The Journal of Organic Chemistry. 75: 4288-91
Sharma V, McLaughlin ML. (2010) Efficient assembly of 2,5,6-substituted pyrimidines via MgI(2)-mediated Morita-Baylis-Hillman reaction. Journal of Combinatorial Chemistry. 12: 327-31
Yi SW, Jain P, Ajmera M, et al. (2009) Cysteine based PNA (CPNA): design and synthesis of novel CPNA monomers. Advances in Experimental Medicine and Biology. 611: 553-4
Anderson L, Topper M, Jain P, et al. (2009) Synthesis of N-Boc protected hydrazine diacids as key structural units for the formation of alpha-helix mimics. Advances in Experimental Medicine and Biology. 611: 211-2
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