Mary K. Froemming, Ph.D.

Affiliations: 
2008 Columbia University, New York, NY 
Area:
organic synthesis
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Dalibor Sames grad student 2008 Columbia
 (Harnessing substrate-enzyme plasticity: Development of fluorogenic reporters for imaging metabolism by the beta-oxidation enzymes.)
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Publications

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Muirhead KE, Froemming M, Li X, et al. (2010) (-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells. Acs Chemical Biology. 5: 1105-14
Froemming MK, Sames D. (2007) Harnessing functional plasticity of enzymes: a fluorogenic probe for imaging 17beta-HSD10 dehydrogenase, an enzyme involved in Alzheimer's and Parkinson's diseases. Journal of the American Chemical Society. 129: 14518-22
Froemming MK, Sames D. (2006) Fluoromorphic substrates for fatty acid metabolism: highly sensitive probes for mammalian medium-chain acyl-CoA dehydrogenase. Angewandte Chemie (International Ed. in English). 45: 637-42
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