Desirae Leipply, Ph.D.

Affiliations: 
2010 Johns Hopkins University, Baltimore, MD 
Area:
RNA folding
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"Desirae Leipply"
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David E. Draper grad student 2010 Johns Hopkins
 (Exploring the thermodynamics of the diversity of divalent magnesium ion interactions with native, partially folded, and unfolded RNA structures.)
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Feller S, Mullenbach T, Franke M, et al. (2012) Structure and properties of barium and calcium borosilicate glasses Physics and Chemistry of Glasses: European Journal of Glass Science and Technology Part B. 53: 210-218
Leipply D, Draper DE. (2011) Evidence for a thermodynamically distinct Mg2+ ion associated with formation of an RNA tertiary structure. Journal of the American Chemical Society. 133: 13397-405
Leipply D, Draper DE. (2011) Effects of Mg2+ on the free energy landscape for folding a purine riboswitch RNA. Biochemistry. 50: 2790-9
Lambert D, Leipply D, Draper DE. (2010) The osmolyte TMAO stabilizes native RNA tertiary structures in the absence of Mg2+: evidence for a large barrier to folding from phosphate dehydration. Journal of Molecular Biology. 404: 138-57
Leipply D, Draper DE. (2010) Dependence of RNA tertiary structural stability on Mg2+ concentration: interpretation of the Hill equation and coefficient. Biochemistry. 49: 1843-53
Leipply D, Lambert D, Draper DE. (2009) Ion-RNA interactions thermodynamic analysis of the effects of mono- and divalent ions on RNA conformational equilibria. Methods in Enzymology. 469: 433-63
Lambert D, Leipply D, Shiman R, et al. (2009) The influence of monovalent cation size on the stability of RNA tertiary structures. Journal of Molecular Biology. 390: 791-804
Leipply D, Melhus BA, Leonardo MR, et al. (2006) Development of functional borate glass surfaces to inhibit bacterial growth Glass Technology: European Journal of Glass Science and Technology Part A. 47: 127-132
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