Ahmed M. Hafez, Ph.D.

Affiliations: 
2004 Johns Hopkins University, Baltimore, MD 
Area:
Synthetic Organic Chemistry and Catalysis
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"Ahmed Hafez"
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Thomas Lectka grad student 2004 Johns Hopkins
 (Generation of highly reactive ketenes and their synthetic utility as intermediates in the asymmetric synthesis of biologically active molecules.)
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Publications

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Wack H, France S, Hafez AM, et al. (2004) Development of a new dimeric cyclophane ligand: application to enhanced diastereo- and enantioselectivity in the catalytic synthesis of beta-lactams. The Journal of Organic Chemistry. 69: 4531-3
France S, Wack H, Taggi AE, et al. (2004) Catalytic, asymmetric alpha-chlorination of acid halides. Journal of the American Chemical Society. 126: 4245-55
Hafez AM, Dudding T, Wagerle TR, et al. (2003) A multistage, one-pot procedure mediated by a single catalyst: a new approach to the catalytic asymmetric synthesis of beta-amino acids. The Journal of Organic Chemistry. 68: 5819-25
Taggi AE, Hafez AM, Lectka T. (2003) Alpha-imino esters: versatile substrates for the catalytic, asymmetric synthesis of alpha- and beta-amino acids and beta-lactams. Accounts of Chemical Research. 36: 10-9
Hafez AM, Taggi AE, Lectka T. (2002) Sequential column asymmetric catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 4114-9
Taggi AE, Hafez AM, Wack H, et al. (2002) The development of the first catalyzed reaction of ketenes and imines: catalytic, asymmetric synthesis of beta-lactams. Journal of the American Chemical Society. 124: 6626-35
France S, Wack H, Hafez AM, et al. (2002) Bifunctional asymmetric catalysis: a tandem nucleophile/Lewis acid promoted synthesis of beta-lactams. Organic Letters. 4: 1603-5
Taggi AE, Wack H, Hafez AM, et al. (2002) Generation of ketenes from acid chlorides using NaH/crown ether shuttle-deprotonation for use in asymmetric catalysis. Organic Letters. 4: 627-9
Dudding T, Hafez AM, Taggi AE, et al. (2002) A catalyst that plays multiple roles: asymmetric synthesis of beta-substituted aspartic acid derivatives through a four-stage, one-pot procedure. Organic Letters. 4: 387-90
Taggi AE, Hafez AM, Dudding T, et al. (2002) Molecular mechanics calculations as predictors of enantioselectivity for chiral nucleophile catalyzed reactions Tetrahedron. 58: 8351-8356
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