Michael T. Scerba, Ph.D.
Affiliations: | 2011 | Johns Hopkins University, Baltimore, MD |
Area:
Synthetic Organic Chemistry and CatalysisGoogle:
"Michael Scerba"Mean distance: 8.45 | S | N | B | C | P |
Parents
Sign in to add mentor| Thomas Lectka | grad student | 2011 | Johns Hopkins | |
| (1.) Charged Nitrogen Hydride-Fluorine Hydrogen Bonding in a Fluorinated Proton Sponge Derivative: Integration of Solution, Solid State, Gas Phase and Computational Studies 2.) Polyfunctional, Asymmetric Reactions of Chiral Ketene Enolates 3.) Catalysis In) | ||||
| Daniel H. Appella | post-doc | 2016 | NIH | |
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Publications
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| Robello M, Nikolayevskiy H, Scerba MT, et al. (2023) Prodrug Strategy Extends the Use of Anti-HIV Sulfanylbenzamides for Application . Acs Pharmacology & Translational Science. 7: 259-273 |
| Nikolayevskiy H, Robello M, Scerba MT, et al. (2019) The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target. European Journal of Medicinal Chemistry. 178: 818-837 |
| Miller Jenkins LM, Paine E, Deshmukh L, et al. (2019) Inhibition of HIV Maturation via Selective Unfolding and Crosslinking of Gag Polyprotein by a Mercaptobenzamide Acetylator. Journal of the American Chemical Society |
| Nikolayevskiy H, Scerba MT, Deschamps JR, et al. (2018) Reaction Kinetics Direct a Rational Synthesis of an HIV-1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity. Chemistry (Weinheim An Der Bergstrasse, Germany) |
| Saha M, Scerba MT, Shank NI, et al. (2017) Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7. Chemmedchem |
| Struble MD, Holl MG, Scerba MT, et al. (2015) Search for a Symmetrical C-F-C Fluoronium Ion in Solution: Kinetic Isotope Effects, Synthetic Labeling, and Computational, Solvent, and Rate Studies. Journal of the American Chemical Society. 137: 11476-90 |
| Struble MD, Scerba MT, Siegler M, et al. (2013) Evidence for a symmetrical fluoronium ion in solution. Science (New York, N.Y.). 340: 57-60 |
| Deblase AF, Scerba MT, Lectka T, et al. (2013) Vibrational predissociation spectroscopy of Ar-tagged, trisubstituted silyl cations Chemical Physics Letters. 568: 9-13 |
| Scerba MT, DeBlase AF, Bloom S, et al. (2012) Characterization of highly unusual NH+-O hydrogen bonding to ester ether oxygen atoms through spectroscopic and computational studies. The Journal of Physical Chemistry. A. 116: 3556-60 |
| Scerba MT, Bloom S, Haselton N, et al. (2012) Interaction of a C-F bond with the π-system of a C═C bond or "head on" with a proximate C-H bond. The Journal of Organic Chemistry. 77: 1605-9 |