Christopher M. Pavlos, Ph.D.

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
nanosecond time-resolved infrared (TRIR) spectroscopy
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"Christopher Pavlos"
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John P. Toscano grad student 2006 Johns Hopkins
 (Diazeniumdiolates: Photochemistry, thermal chemistry, and their use as potential heart failure therapeutics.)
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Publications

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Thorpe C, De Arras L, Toscano JP, et al. (2009) The Role of Phospholamban Cysteines in the Activation of the Cardiac Sarcoplasmic Reticulum Calcium Pump by Nitroxyl Biophysical Journal. 96: 326a
Froehlich JP, Mahaney JE, Keceli G, et al. (2008) Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl. Biochemistry. 47: 13150-2
Zhu Y, Pavlos CM, Toscano JP, et al. (2006) 8-Bromo-7-hydroxyquinoline as a photoremovable protecting group for physiological use: mechanism and scope. Journal of the American Chemical Society. 128: 4267-76
Pavlos CM, Xu H, Toscano JP. (2005) Photosensitive precursors to nitric oxide. Current Topics in Medicinal Chemistry. 5: 637-47
Hagen V, Benndorf K, Kaupp UB, et al. (2005) Control of Cellular Activity Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules. 155-251
Pavlos CM, Xu H, Toscano JP. (2004) Controlled photochemical release of nitric oxide from O2-substituted diazeniumdiolates. Free Radical Biology & Medicine. 37: 745-52
Pavlos CM, Cohen AD, D'Sa RA, et al. (2003) Photochemistry of 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate: an experimental and computational investigation. Journal of the American Chemical Society. 125: 14934-40
Bushan KM, Xu H, Ruane PH, et al. (2002) Controlled photochemical release of nitric oxide from O(2)-naphthylmethyl- and O(2)-naphthylallyl-substituted diazeniumdiolates. Journal of the American Chemical Society. 124: 12640-1
Ruane PH, Bushan KM, Pavlos CM, et al. (2002) Controlled photochemical release of nitric oxide from O2-benzyl-substituted diazeniumdiolates. Journal of the American Chemical Society. 124: 9806-11
Bushan KM, Xu H, Ruane PH, et al. (2002) Controlled photochemical release of nitric oxide from O2-naphthylmethyl- and O2-naphthylallyl-substituted diazeniumdiolates Journal of the American Chemical Society. 124: 12640-12641
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