Jonathan M. Caruthers, Ph.D.

Affiliations: 
2000 University of Pennsylvania, Philadelphia, PA, United States 
Area:
structure-mechanism of hydrolytic metalloenzymes
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"Jonathan Caruthers"
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David W. Christianson grad student 2000 Penn
 (Aristolochene synthase structure and function.)
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Publications

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Axelrod HL, Kozbial P, McMullan D, et al. (2010) Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1347-53
Han GW, Yang XL, McMullan D, et al. (2010) Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1326-34
Krishna SS, Aravind L, Bakolitsa C, et al. (2010) The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1160-6
Verlinde CL, Fan E, Shibata S, et al. (2009) Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium. Current Topics in Medicinal Chemistry. 9: 1678-87
Xu Q, Sudek S, McMullan D, et al. (2009) Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase. Structure (London, England : 1993). 17: 303-13
Fan E, Baker D, Fields S, et al. (2008) Structural genomics of pathogenic protozoa: an overview. Methods in Molecular Biology (Clifton, N.J.). 426: 497-513
Caruthers JM, Hu Y, McKay DB. (2006) Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1191-5
Caruthers JM, Feng Y, McKay DB, et al. (2006) Retention of core catalytic functions by a conserved minimal ribonuclease E peptide that lacks the domain required for tetramer formation. The Journal of Biological Chemistry. 281: 27046-51
Robien MA, Bosch J, Buckner FS, et al. (2006) Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site. Proteins. 62: 570-7
Caruthers J, Bosch J, Buckner F, et al. (2006) Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum. Proteins. 62: 338-42
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