Kevin Jude, Ph.D.

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
structure-mechanism of hydrolytic metalloenzymes
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"Kevin Jude"
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Parents

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Loren Dean Williams research assistant Georgia Tech
David W. Christianson grad student 2007 Penn
 (Crystallography at ultrahigh and infralow resolution: Studies of carbonic anhydrase and ribonuclease P.)
James M. Berger post-doc UC Berkeley
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Publications

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Jude KM, Hartland A, Berger JM. (2013) Real-time detection of DNA topological changes with a fluorescently labeled cruciform. Nucleic Acids Research. 41: e133
Hanes MS, Jude KM, Berger JM, et al. (2009) Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. Biochemistry. 48: 9185-93
Aaron JA, Chambers JM, Jude KM, et al. (2008) Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. Journal of the American Chemical Society. 130: 6942-3
Srivastava DK, Jude KM, Banerjee AL, et al. (2007) Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II. Journal of the American Chemical Society. 129: 5528-37
Jude KM, Banerjee AL, Haldar MK, et al. (2006) Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity. Journal of the American Chemical Society. 128: 3011-8
Colleluori DM, Reczkowski RS, Emig FA, et al. (2005) Probing the role of the hyper-reactive histidine residue of arginase. Archives of Biochemistry and Biophysics. 444: 15-26
Jude KM, Wright SK, Tu C, et al. (2002) Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle. Biochemistry. 41: 2485-91
Presnell SR, Patil GS, Mura C, et al. (1998) Oxyanion-mediated inhibition of serine proteases. Biochemistry. 37: 17068-81
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