Kevin Jude, Ph.D.

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
structure-mechanism of hydrolytic metalloenzymes
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Loren Dean Williams research assistant Georgia Tech
David W. Christianson grad student 2007 Penn
 (Crystallography at ultrahigh and infralow resolution: Studies of carbonic anhydrase and ribonuclease P.)
James M. Berger post-doc UC Berkeley
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Publications

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Weiskopf K, Jahchan NS, Schnorr PJ, et al. (2016) CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation
Moraga I, Richter D, Wilmes S, et al. (2015) Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Science Signaling. 8: ra114
Spangler JB, Tomala J, Luca VC, et al. (2015) Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity. 42: 815-25
Burg JS, Ingram JR, Venkatakrishnan AJ, et al. (2015) Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor. Science (New York, N.Y.). 347: 1113-7
Luca VC, Jude KM, Pierce NW, et al. (2015) Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science (New York, N.Y.). 347: 847-53
Jude KM, Hartland A, Berger JM. (2013) Real-time detection of DNA topological changes with a fluorescently labeled cruciform. Nucleic Acids Research. 41: e133
Hanes MS, Jude KM, Berger JM, et al. (2009) Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. Biochemistry. 48: 9185-93
Aaron JA, Chambers JM, Jude KM, et al. (2008) Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. Journal of the American Chemical Society. 130: 6942-3
Srivastava DK, Jude KM, Banerjee AL, et al. (2007) Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II. Journal of the American Chemical Society. 129: 5528-37
Jude KM, Banerjee AL, Haldar MK, et al. (2006) Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity. Journal of the American Chemical Society. 128: 3011-8
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