Jin Wen, Ph.D.

Affiliations: 
2002 Iowa State University, Ames, IA, United States 
Area:
Physical, Biophysical, Analytical Chemistry
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"Jin Wen"
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Jacob W. Petrich grad student 2002 Iowa State
 (The applications of laser spectroscopy in analytical chemistry and biochemistry: Investigating the photophysics of hypericin and hypocrellin, as well as the structure of porcine fructose -1,6 -bisphosphatase.)
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Publications

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Wen J, Bao Y, Niu Q, et al. (2016) Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy. European Journal of Medicinal Chemistry. 109: 350-359
Wen J, Chowdhury P, Fulton DB, et al. (2003) Does solvent influence the ground-state tautomeric population of hypericin? Photochemistry and Photobiology. 77: 5-9
Ashby KD, Wen J, Chowdhury P, et al. (2003) Fluorescence of dietary porphyrins as a basis for real-time detection of fecal contamination on meat. Journal of Agricultural and Food Chemistry. 51: 3502-7
Wen J, Chowdhury P, Wills NJ, et al. (2002) Toward the molecular flashlight: preparation, properties, and photophysics of a hypericin-luciferin tethered molecule. Photochemistry and Photobiology. 76: 153-7
Wen J, Nelson SW, Honzatko RB, et al. (2001) Environment of tryptophan 57 in porcine fructose-1,6-bisphosphatase studied by time-resolved fluorescence and site-directed mutagenesis. Photochemistry and Photobiology. 74: 679-85
Wills NJ, Park J, Wen J, et al. (2001) Tumor cell toxicity of hypericin and related analogs. Photochemistry and Photobiology. 74: 216-20
Datta A, Bandyopadhyay P, Wen J, et al. (2001) Coupling of large-amplitude side chain motions to the excited-state H-atom transfer of perylene quinones: Application of theory and experiment to calphostin C Journal of Physical Chemistry A. 105: 1057-1060
Datta A, Smirnov AV, Wen J, et al. (2000) Multidimensional reaction coordinate for the excited-state H-atom transfer in perylene quinones: importance of the 7-membered ring in hypocrellins A and B. Photochemistry and Photobiology. 71: 166-72
Das K, Smirnov AV, Wen J, et al. (1999) Photophysics of hypericin and hypocrellin A in complex with subcellular components: interactions with human serum albumin. Photochemistry and Photobiology. 69: 633-45
Das K, Ashby KD, Wen J, et al. (1999) Temperature dependence of the excited-state intramolecular proton transfer reaction in hypericin and hypocrellin A Journal of Physical Chemistry B. 103: 1581-1585
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