Robert M. Culik, Ph.D.

Affiliations: 
2014 Biochemistry and Molecular Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Area:
Physical and Biological Chemistry
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"Robert Culik"
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Feng Gai grad student 2014 Penn
 (Infrared measurements of protein conformational dynamics.)
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Publications

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Culik RM, Sekhar A, Nagesh J, et al. (2018) Effects of maturation on the conformational free-energy landscape of SOD1. Proceedings of the National Academy of Sciences of the United States of America
Abaskharon RM, Culik RM, Woolley GA, et al. (2015) Tuning the Attempt Frequency of Protein Folding Dynamics via Transition-State Rigidification: Application to Trp-cage. The Journal of Physical Chemistry Letters. 6: 521-526
Ma J, Pazos IM, Zhang W, et al. (2015) Site-specific infrared probes of proteins. Annual Review of Physical Chemistry. 66: 357-77
Markiewicz BN, Culik RM, Gai F. (2014) Tightening up the structure, lighting up the pathway: Application of molecular constraints and light to manipulate protein folding, self-assembly and function. Science China. Chemistry. 57: 1615-1624
Culik RM, Abaskharon RM, Pazos IM, et al. (2014) Experimental validation of the role of trifluoroethanol as a nanocrowder. The Journal of Physical Chemistry. B. 118: 11455-61
Markiewicz BN, Yang L, Culik RM, et al. (2014) How quickly can a β-hairpin fold from its transition state? The Journal of Physical Chemistry. B. 118: 3317-25
Culik RM, Annavarapu S, Nanda V, et al. (2013) Using D-Amino Acids to Delineate the Mechanism of Protein Folding: Application to Trp-cage. Chemical Physics. 422
Markiewicz BN, Jo H, Culik RM, et al. (2013) Assessment of local friction in protein folding dynamics using a helix cross-linker. The Journal of Physical Chemistry. B. 117: 14688-96
Lin CW, Culik RM, Gai F. (2013) Using VIPT-jump to distinguish between different folding mechanisms: application to BBL and a Trpzip. Journal of the American Chemical Society. 135: 7668-73
Culik RM, Jo H, DeGrado WF, et al. (2012) Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding. Journal of the American Chemical Society. 134: 8026-9
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