William C. Ho, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biological Chemistry
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"William Ho"
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Ronen Marmorstein grad student 2006 Penn
 (Structural studies of the mouse p53 DNA binding domain in the presence and absence of DNA.)
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Publications

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Malecka KA, Ho WC, Marmorstein R. (2009) Crystal structure of a p53 core tetramer bound to DNA. Oncogene. 28: 325-33
Ho WC, Luo C, Zhao K, et al. (2006) High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallographica. Section D, Biological Crystallography. 62: 1484-93
Ho WC, Fitzgerald MX, Marmorstein R. (2006) Structure of the p53 core domain dimer bound to DNA. The Journal of Biological Chemistry. 281: 20494-502
Wang W, Ho WC, Dicker DT, et al. (2005) Acridine derivatives activate p53 and induce tumor cell death through Bax. Cancer Biology & Therapy. 4: 893-8
Mo Y, Ho W, Johnston K, et al. (2001) Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. Journal of Molecular Biology. 314: 495-506
Ho WC, Steinbeck C, Richert C. (1999) Solution structure of the aminoacyl-capped oligodeoxyribonucleotide duplex (W-TGCGCAC)(2). Biochemistry. 38: 12597-606
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