Michael Brent, Ph.D.
Affiliations: | 2009 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Biological ChemistryGoogle:
"Michael Brent"Mean distance: 9.66 | S | N | B | C | P |
Parents
Sign in to add mentor| Ronen Marmorstein | grad student | 2009 | Penn | |
| (Acetyltransfer in gene regulation: Structural and biochemical studies of human SIRT1 deacetylase, its FoxO1 substrate, and archaeal PAT acetyltransferase.) | ||||
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Publications
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| Pan M, Yuan H, Brent M, et al. (2012) SIRT1 contains N- and C-terminal regions that potentiate deacetylase activity. The Journal of Biological Chemistry. 287: 2468-76 |
| Sanders BD, Jackson B, Brent M, et al. (2009) Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & Medicinal Chemistry. 17: 7031-41 |
| Brent MM, Iwata A, Carten J, et al. (2009) Structure and biochemical characterization of protein acetyltransferase from Sulfolobus solfataricus. The Journal of Biological Chemistry. 284: 19412-9 |
| Brent MM, Anand R, Marmorstein R. (2008) Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure (London, England : 1993). 16: 1407-16 |
| Anand R, Kim AY, Brent M, et al. (2008) Biochemical analysis of MST1 kinase: elucidation of a C-terminal regulatory region. Biochemistry. 47: 6719-26 |
| Kwon HS, Brent MM, Getachew R, et al. (2008) Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host & Microbe. 3: 158-67 |
| Brent MM, Marmorstein R. (2008) Ankyrin for methylated lysines. Nature Structural & Molecular Biology. 15: 221-2 |