Matthew S. Kelker, Ph.D.
Affiliations: | 2005 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Structural biology, immunology, X-ray crystallographyGoogle:
"Matthew Kelker"Mean distance: 9.37 | S | N | B | C | P |
Parents
Sign in to add mentor| Ian A. Wilson | grad student | 2005 | Scripps Institute | |
| (Structural and biophysical studies of human and mouse TREM -1 and the use of multi-wavelength anomalous dispersion to phase merohedrally-twinned crystals.) | ||||
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Publications
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| Dementiev A, Board J, Sitaram A, et al. (2016) The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins. Bmc Biology. 14: 71 |
| Kelker MS, Berry C, Evans SL, et al. (2014) Structural and biophysical characterization of Bacillus thuringiensis insecticidal proteins Cry34Ab1 and Cry35Ab1. Plos One. 9: e112555 |
| Kelker MS, Page R, Peti W. (2009) Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors. Journal of Molecular Biology. 385: 11-21 |
| Kelker MS, Dancheck B, Ju T, et al. (2007) Structural basis for spinophilin-neurabin receptor interaction. Biochemistry. 46: 2333-44 |
| Choe J, Kelker MS, Wilson IA. (2005) Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science (New York, N.Y.). 309: 581-5 |
| Wiseman RL, Johnson SM, Kelker MS, et al. (2005) Kinetic stabilization of an oligomeric protein by a single ligand binding event. Journal of the American Chemical Society. 127: 5540-51 |
| Foss TR, Kelker MS, Wiseman RL, et al. (2005) Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis. Journal of Molecular Biology. 347: 841-54 |
| Kelker MS, Debler EW, Wilson IA. (2004) Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A. Journal of Molecular Biology. 344: 1175-81 |
| Kelker MS, Foss TR, Peti W, et al. (2004) Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A. Journal of Molecular Biology. 342: 1237-48 |
| Rudolph MG, Kelker MS, Schneider TR, et al. (2003) Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallographica. Section D, Biological Crystallography. 59: 290-8 |