Kristopher M. Kuchenbecker, Ph.D.
Affiliations: | 2013 | Biophysics | University of California, San Francisco, San Francisco, CA |
Area:
X-ray crystal structures of nuclear receptors, kinesin molecular motors, clathrin, and many enzymesGoogle:
"Kristopher Kuchenbecker"Mean distance: 8.41 | S | N | B | C | P |
Parents
Sign in to add mentor| Robert J. Fletterick | grad student | 2013 | UCSF | |
| (Allosteric Regulation of Promiscuous Surfaces.) | ||||
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Publications
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| Cortez FJ, Nguyen P, Truillet C, et al. (2017) Development of 5N-Bicalutamide, A High-affinity Reversible Covalent Antiandrogen. Acs Chemical Biology |
| Torres IO, Kuchenbecker KM, Nnadi CI, et al. (2015) Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism. Nature Communications. 6: 6204 |
| Blind RD, Sablin EP, Kuchenbecker KM, et al. (2014) The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 15054-9 |
| Das D, Yumoto F, Kuchenbecker K, et al. (2014) Understanding disease mutations from the crystal structure of SOX9 with DNA Acta Crystallographica Section a Foundations and Advances. 70: C1398-C1398 |
| Bravo DT, Yang YL, Kuchenbecker K, et al. (2013) Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer. Bmc Cancer. 13: 316 |
| Watson LC, Kuchenbecker KM, Schiller BJ, et al. (2013) The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals. Nature Structural & Molecular Biology. 20: 876-83 |
| Bravo D, Xu Z, Kuchenbecker K, et al. (2012) Abstract 3238: Frizzled-8 receptor is activated by the Wnt-2 ligant in non-small cell lung cancer Cancer Research. 72: 3238-3238 |
| Shi Y, He B, Kuchenbecker KM, et al. (2007) Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells. International Journal of Cancer. Journal International Du Cancer. 121: 1175-81 |
| Lin YC, You L, Xu Z, et al. (2007) Wnt inhibitory factor-1 gene transfer inhibits melanoma cell growth. Human Gene Therapy. 18: 379-86 |
| Batra S, Shi Y, Kuchenbecker KM, et al. (2006) Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma. Biochemical and Biophysical Research Communications. 342: 1228-32 |