Gregory R. Hoffman, Ph.D.

Affiliations: 
2002 Cornell University, Ithaca, NY, United States 
Area:
Signal Transduction Mechanisms
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"Gregory Hoffman"
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Richard A. Cerione grad student 2002 Cornell
 (The structural basis of Cdc42-mediated signal transduction.)
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Publications

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DeRegis CJ, Rahl PB, Hoffman GR, et al. (2008) Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. Bmc Cell Biology. 9: 3
Hoffman GR, Rahl PB, Collins RN, et al. (2003) Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain. Molecular Cell. 12: 615-25
Hoffman GR, Cerione RA. (2002) Signaling to the Rho GTPases: networking with the DH domain. Febs Letters. 513: 85-91
Hoffman GR, Cerione RA. (2001) Rac inserts its way into the immune response. Nature Immunology. 2: 194-6
Hoffman GR, Cerione RA. (2000) Flipping the switch: the structural basis for signaling through the CRIB motif. Cell. 102: 403-6
Hoffman GR, Nassar N, Cerione RA. (2000) Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell. 100: 345-56
Nassar N, Hoffman GR, Manor D, et al. (1998) Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nature Structural Biology. 5: 1047-52
Hoffman GR, Nassar N, Oswald RE, et al. (1998) Fluoride activation of the Rho family GTP-binding protein Cdc42Hs. The Journal of Biological Chemistry. 273: 4392-9
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