Robin J. Rosenfeld, Ph.D.

Affiliations: 
2002 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
protein recognition, interaction and catalysis
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"Robin Rosenfeld"
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Parents

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Elizabeth D. Getzoff grad student 2002 Scripps Institute
 (Nitric oxide synthase: Structural and computational analyses of inhibitor potency and biophysical studies of nitrosylated NOS intermediates.)
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Publications

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Rosenfeld R, Garcin E, Arvai A, et al. (2012) Nitric oxide synthases in motion Nitric Oxide. 27: S25
Rosenfeld RJ, Bonaventura J, Szymczyna BR, et al. (2010) Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation. The Journal of Biological Chemistry. 285: 31581-9
Perryman AL, Zhang Q, Soutter HH, et al. (2010) Fragment-based screen against HIV protease. Chemical Biology & Drug Design. 75: 257-68
Garcin ED, Arvai AS, Rosenfeld RJ, et al. (2008) Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nature Chemical Biology. 4: 700-7
Rastelli G, Rosenfeld R, Reid R, et al. (2008) Molecular modeling and crystal structure of ERK2-hypothemycin complexes Journal of Structural Biology. 164: 18-23
Heaslet H, Rosenfeld R, Giffin M, et al. (2007) Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallographica. Section D, Biological Crystallography. 63: 866-75
Garcin-Hosfield ED, Arvai AS, Rosenfeld RJ, et al. (2006) P188. Structural insights into NOS regulatory mechanisms: What? where? how? Nitric Oxide. 14: 77-78
Garcin-Hosfield E, Arvai A, Rosenfeld R, et al. (2006) P0118. Structural insights into the conformational selectivity of inducible nitric oxide synthase specific inhibitors Nitric Oxide. 14: 55
Connolly S, Aberg A, Arvai A, et al. (2004) 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. Journal of Medicinal Chemistry. 47: 3320-3
Rosenfeld RJ, Goodsell DS, Musah RA, et al. (2003) Automated docking of ligands to an artificial active site: augmenting crystallographic analysis with computer modeling. Journal of Computer-Aided Molecular Design. 17: 525-36
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