Daniel A. Keedy, Ph.D.
Affiliations: | 2012 | Biochemistry | Duke University, Durham, NC |
Area:
3D structures of proteinsGoogle:
"Daniel Keedy"Mean distance: 8.76 | S | N | B | C | P |
Parents
Sign in to add mentorDavid C. Richardson | grad student | 2012 | Duke | |
(Using Protein-Likeness to Validate Conformational Alternatives.) |
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Publications
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Mehlman TS, Ginn HM, Keedy DA. (2024) An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv : the Preprint Server For Biology |
Sharma S, Skaist Mehlman T, Sagabala RS, et al. (2024) High-resolution double vision of the allosteric phosphatase PTP1B. Acta Crystallographica. Section F, Structural Biology Communications. 80: 1-12 |
Wankowicz SA, Ravikumar A, Sharma S, et al. (2023) Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM. Biorxiv : the Preprint Server For Biology |
Sharma S, Ebrahim A, Keedy DA. (2023) Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B. Acta Crystallographica. Section F, Structural Biology Communications. 79: 23-30 |
Riley BT, Wankowicz SA, de Oliveira SHP, et al. (2020) qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps. Protein Science : a Publication of the Protein Society |
Keedy DA. (2019) Journey to the center of the protein: allostery from multitemperature multiconformer X-ray crystallography. Acta Crystallographica. Section D, Structural Biology. 75: 123-137 |
van Zundert G, Hudson BM, de Oliveira S, et al. (2018) qFit-ligand reveals widespread conformational heterogeneity of drug-like molecules in X-ray electron density maps. Journal of Medicinal Chemistry |
Keedy DA, Hill ZB, Biel JT, et al. (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife. 7 |
Williams CJ, Headd JJ, Moriarty NW, et al. (2017) MolProbity: More and better reference data for improved all-atom structure validation. Protein Science : a Publication of the Protein Society |
Babcock NS, Sivak DA, Keedy D, et al. (2017) Model Comparison to Identify Structural Heterogeneity in Protein X-Ray Crystallography Biophysical Journal. 112: 486a |