Chenglong Li, Ph.D.

Affiliations: 
2000 Cornell University, Ithaca, NY, United States 
 2005-2016 Ohio State University, Columbus, Columbus, OH 
 2016- University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Structure and function of proteins using X-ray crystallography
Website:
http://pharmacy.ufl.edu/faculty/chenglong-li/
Google:
"Chenglong Li"
Mean distance: 13.3
 
SNBCP

Parents

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Steven E. Ealick grad student 2000 Cornell
 (Crystal structure of Escherichia coli aminoimidazole ribonucleotide synthetase at 2.5 angstrom resolution and x-ray crystallographic analysis of E. coli purine nucleoside phosphorylase/ligand complexes.)

Children

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Kiran V. Mahasenan grad student 2012 Ohio State (Physics Tree)
Wenying Yu grad student 2013 Ohio State (Physics Tree)
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Publications

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Pan L, Chen X, Rassool FV, et al. (2022) LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells. Biomedicines. 10
Pan L, Zhang R, Ma L, et al. (2021) STAT3 inhibitor in combination with irradiation significantly inhibits cell viability, cell migration, invasion and tumorsphere growth of human medulloblastoma cells. Cancer Biology & Therapy. 1-10
Zhang R, Yang X, Roque DM, et al. (2021) A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin. Plos One. 16: e0240145
Chen X, Pan L, Wei J, et al. (2021) LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells. Scientific Reports. 11: 6517
Pan L, Chen X, Fu S, et al. (2020) LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer. Breast Cancer Research and Treatment
Al-Awadhi FH, Gao B, Rezaei MA, et al. (2018) Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium. Journal of Medicinal Chemistry
Chen X, Wei J, Li C, et al. (2017) Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells. International Journal of Oncology
Liu T, Ma H, Shi W, et al. (2017) Inhibition of STAT3 signaling pathway by ursolic acid suppresses growth of hepatocellular carcinoma. International Journal of Oncology. 51: 555-562
Wang Y, Ma H, Zhao C, et al. (2017) Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling. Oncotarget
Sugimoto Y, Sawant DB, Fisk HA, et al. (2017) Novel pyrrolopyrimidines as Mps1/TTK kinase inhibitors for breast cancer. Bioorganic & Medicinal Chemistry
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