Christopher T. Jurgenson, Ph.D.

Affiliations: 
2008 Cornell University, Ithaca, NY, United States 
Area:
structure and function of proteins using X-ray crystallography
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"Christopher Jurgenson"
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Steven E. Ealick grad student 2008 Cornell
 (X-ray crystallographic studies of enzymes found in the biosynthetic pathways of thiamin and cysteine, and the purine nucleoside phosphorylase salvage pathway.)
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Publications

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Jurgenson CT, Ealick SE, Begley TP. (2009) Biosynthesis of Thiamin Pyrophosphate. Ecosal Plus. 3
Jurgenson CT, Begley TP, Ealick SE. (2009) The structural and biochemical foundations of thiamin biosynthesis. Annual Review of Biochemistry. 78: 569-603
O'Leary SE, Jurgenson CT, Ealick SE, et al. (2008) O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis. Biochemistry. 47: 11606-15
Jurgenson CT, Burns KE, Begley TP, et al. (2008) Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis. Biochemistry. 47: 10354-64
Chatterjee A, Schroeder FC, Jurgenson CT, et al. (2008) Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate. Journal of the American Chemical Society. 130: 11394-8
Chatterjee A, Jurgenson CT, Schroeder FC, et al. (2007) Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate. Journal of the American Chemical Society. 129: 2914-22
Jurgenson CT, Chatterjee A, Begley TP, et al. (2006) Structural insights into the function of the thiamin biosynthetic enzyme Thi4 from Saccharomyces cerevisiae. Biochemistry. 45: 11061-70
Chatterjee A, Jurgenson CT, Schroeder FC, et al. (2006) Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis. Journal of the American Chemical Society. 128: 7158-9
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