Xuling Zhu, Ph.D.

Affiliations: 
2011 Cornell University, Ithaca, NY, United States 
Area:
chemistry, biology, and application of enzymes
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"Xuling Zhu"
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Parents

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Hening Lin grad student 2011 Cornell
 (Diphthamide biosynthesis: Characterization and mechanistic studies of an unconventional radical SAM enzyme PhDph2.)
Priscilla L. Yang post-doc Harvard
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Publications

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Karadagi A, Cavedon AG, Zemack H, et al. (2020) Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency. Scientific Reports. 10: 7052
de Wispelaere M, Lian W, Potisopon S, et al. (2018) Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology
Clark MJ, Miduturu C, Schmidt AG, et al. (2016) GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein. Cell Chemical Biology. 23: 443-452
Dong M, Su X, Dzikovski B, et al. (2014) Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis. Journal of the American Chemical Society. 136: 1754-7
Jiang H, Sherwood R, Zhang S, et al. (2013) Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry. Analytical Biochemistry. 433: 218-26
Zhu X, Dzikovski B, Su X, et al. (2011) Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis. Molecular Biosystems. 7: 74-81
Zhang Y, Zhu X, Torelli AT, et al. (2011) Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme (Nature (2010) 465 (891-896)) Nature. 473: 544
Zhu X, Kim J, Su X, et al. (2010) Reconstitution of diphthine synthase activity in vitro. Biochemistry. 49: 9649-57
Zhang Y, Zhu X, Torelli AT, et al. (2010) Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature. 465: 891-6
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