Jeffrey C. Kurz, Ph.D.

Affiliations: 
2001 Duke University, Durham, NC 
Area:
Enzymology, metalloenzymes, ribozyme, RNA
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"Jeffrey Kurz"
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Carol A. Fierke grad student 2001 Duke
 (Role of the protein component of Bacillus subtilis RNase P: Specific stabilization of precursor tRNA and metal ion interactions.)
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Publications

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Gutsaeva DR, Parkerson JB, Yerigenahally SD, et al. (2011) Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease. Blood. 117: 727-35
Koutmou KS, Zahler NH, Kurz JC, et al. (2010) Protein-precursor tRNA contact leads to sequence-specific recognition of 5' leaders by bacterial ribonuclease P. Journal of Molecular Biology. 396: 195-208
Crary SM, Kurz JC, Fierke CA. (2002) Specific phosphorothioate substitutions probe the active site of Bacillus subtilis ribonuclease P. Rna (New York, N.Y.). 8: 933-47
Kurz JC, Fierke CA. (2002) The affinity of magnesium binding sites in the Bacillus subtilis RNase P x pre-tRNA complex is enhanced by the protein subunit. Biochemistry. 41: 9545-58
Henkels CH, Kurz JC, Fierke CA, et al. (2001) Linked folding and anion binding of the Bacillus subtilis ribonuclease P protein. Biochemistry. 40: 2777-89
Kurz JC, Fierke CA. (2000) Ribonuclease P: a ribonucleoprotein enzyme. Current Opinion in Chemical Biology. 4: 553-8
Niranjanakumari S, Kurz JC, Fierke CA. (1998) Expression, purification and characterization of the recombinant ribonuclease P protein component from Bacillus subtilis. Nucleic Acids Research. 26: 3090-6
Kurz JC, Niranjanakumari S, Fierke CA. (1998) Protein component of Bacillus subtilis RNase P specifically enhances the affinity for precursor-tRNAAsp. Biochemistry. 37: 2393-400
Fierke CA, Crarv SM, Kurz JC, et al. (1997) Ribonuclease P: Function of magnesium ions and protein subunit Faseb Journal. 11: A852
Beebe JA, Kurz JC, Fierke CA. (1996) Magnesium ions are required by Bacillus subtilis ribonuclease P RNA for both binding and cleaving precursor tRNAAsp. Biochemistry. 35: 10493-505
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