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Laura K. Henchey, Ph.D.

Affiliations: 
2010 Chemistry New York University, New York, NY, United States 
Area:
Bioorganic Chemistry
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"Laura Henchey"
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Paramjit S. Arora grad student 2010 NYU
 (Mimicking alpha-helical transactivation domains with hydrogen bond surrogate derived artificial alpha-helices.)

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Publications

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Kushal S, Lao BB, Henchey LK, et al. (2013) Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 15602-7
Henchey LK, Kushal S, Dubey R, et al. (2012) Correction to Inhibition of Hypoxia Inducible Factor 1-Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix. Journal of the American Chemical Society. 134: 8000
Kushal S, Bullock B, Henchey L, et al. (2012) Abstract 289: Hydrogen bond surrogate (HBS) helices as orthosteric regulator of hypoxia inducible transcription Cancer Research. 72: 289-289
Henchey LK, Porter JR, Ghosh I, et al. (2010) High specificity in protein recognition by hydrogen-bond-surrogate α-helices: selective inhibition of the p53/MDM2 complex. Chembiochem : a European Journal of Chemical Biology. 11: 2104-7
Henchey LK, Kushal S, Dubey R, et al. (2010) Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix. Journal of the American Chemical Society. 132: 941-3
Block KM, Wang H, Szabó LZ, et al. (2009) Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine. Journal of the American Chemical Society. 131: 18078-88
Henchey LK, Jochim AL, Arora PS. (2008) Contemporary strategies for the stabilization of peptides in the alpha-helical conformation. Current Opinion in Chemical Biology. 12: 692-7
Angelo NG, Henchey LK, Waxman AJ, et al. (2007) Synthesis and characterization of aldol condensation products from unknown aldehydes and ketones. An inquiry-based experiment in the undergraduate laboratory Journal of Chemical Education. 84: 1816-1818
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