John Raymond Hepler
Affiliations: | 1996- | Pharmacology | Emory University School of Medicine, Atlanta, GA, United States |
Area:
G protein signaling, RGS proteins, GPCRWebsite:
http://www.pharm.emory.edu/people/primary/hepler-john.htmlGoogle:
"John Raymond Hepler"Bio:
http://pharmacology.emory.edu/hepler/lab-members/hepler-cv.html
https://scholar.google.com/citations?hl=en&user=tGRPMs4AAAAJ
Mean distance: 15.72 (cluster 6) | S | N | B | C | P |
Cross-listing: Neurotree
Parents
Sign in to add mentor| T. Kendall Harden | grad student | 1988 | UNC Chapel Hill | |
| (Identification and characterization of biochemical mechanisms involved in the regulation of cell surface receptor-mediated stimulation of phosphoinsitide hydrolysis.) | ||||
| Alfred G. Gilman | post-doc | 1990-1996 | UT Southwestern | |
Children
Sign in to add trainee| Mary Rose Branch | research assistant | Emory (Neurotree) | |
| Nicole E. Brown | grad student | Emory (Neurotree) | |
| Paul R. Evans | grad student | Emory (Neurotree) | |
| Kyle Gerber | grad student | Emory (Neurotree) | |
| Katherine E. Squires | grad student | Emory (Neurotree) | |
| Susanne Hollinger | grad student | 2003 | Emory (Neurotree) |
| Katherine H. Pedone | grad student | 2007 | Emory (Neurotree) |
| Kelly L. McCoy | grad student | 2010 | Emory (Neurotree) |
| Christopher P. Vellano | grad student | 2012 | Emory (Neurotree) |
Collaborators
Sign in to add collaborator| Kendall J. Blumer | collaborator | (Neurotree) | |
| Serena M. Dudek | collaborator | (Neurotree) | |
| Ryohei Yasuda | collaborator | (Neurotree) |
BETA: Related publications
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Publications
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| Samadi M, Hales CA, Lustberg DJ, et al. (2023) Mechanisms of mGluR-dependent plasticity in hippocampal area CA2. Hippocampus |
| Montanez-Miranda C, Bramlett SN, Hepler JR. (2022) RGS14 expression in CA2 hippocampus, amygdala, and basal ganglia: Implications for human brain physiology and disease. Hippocampus |
| Montanez-Miranda C, Perszyk RE, Harbin NH, et al. (2022) . Molecular Pharmacology |
| Friedman PA, Sneddon WB, Mamonova T, et al. (2022) RGS14 regulates hormone-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein. The Journal of Biological Chemistry. 101836 |
| Alexander SP, Kelly E, Mathie A, et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. British Journal of Pharmacology. 178: S1-S26 |
| Harbin NH, Bramlett SN, Montanez-Miranda C, et al. (2021) RGS14 Regulation of Post-Synaptic Signaling and Spine Plasticity in Brain. International Journal of Molecular Sciences. 22 |
| Foster SL, Lustberg DJ, Harbin NH, et al. (2021) RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures. Psychopharmacology |
| Squires KE, Gerber KJ, Tillman MC, et al. (2020) Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. 296: 100024 |
| Squires KE, Gerber KJ, Tillman MC, et al. (2020) Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry |
| Gerber KJ, Squires KE, Hepler JR. (2019) Correction: 14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gα-AlF signaling complex and RGS14 nuclear localization. The Journal of Biological Chemistry. 294: 12262 |