Taylor B. Updegrove, Ph.D.

Affiliations: 
2011 Georgia Institute of Technology, Atlanta, GA 
 2016- National Cancer Institute, Rockville, MD, United States 
Area:
RNA; DNA; biophysics
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"Taylor Updegrove"
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Parents

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Roger M. Wartell grad student 2011 Georgia Tech
 (Binding properties of Hfq to RNA and genomic DNA and the functional implications.)
Gisela Storz post-doc 2011-2016 NIH (Microtree)
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Publications

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Updegrove TB, Kouse AB, Bandyra KJ, et al. (2018) Stem-loops direct precise processing of 3' UTR-derived small RNA MicL. Nucleic Acids Research
Hao Y, Updegrove TB, Livingston NN, et al. (2016) Protection against deleterious nitrogen compounds: role of σS-dependent small RNAs encoded adjacent to sdiA. Nucleic Acids Research
Updegrove TB, Zhang A, Storz G. (2016) Hfq: the flexible RNA matchmaker. Current Opinion in Microbiology. 30: 133-138
Updegrove TB, Shabalina SA, Storz G. (2015) How do base-pairing small RNAs evolve? Fems Microbiology Reviews. 39: 379-91
Dambach M, Sandoval M, Updegrove TB, et al. (2015) The ubiquitous yybP-ykoY riboswitch is a manganese-responsive regulatory element. Molecular Cell. 57: 1099-109
Guo MS, Updegrove TB, Gogol EB, et al. (2014) MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein. Genes & Development. 28: 1620-34
Beisel CL, Updegrove TB, Janson BJ, et al. (2012) Multiple factors dictate target selection by Hfq-binding small RNAs. The Embo Journal. 31: 1961-74
Updegrove TB, Wartell RM. (2011) The influence of Escherichia coli Hfq mutations on RNA binding and sRNA•mRNA duplex formation in rpoS riboregulation. Biochimica Et Biophysica Acta. 1809: 532-40
Mezencev R, Updegrove T, Kutschy P, et al. (2011) Camalexin induces apoptosis in T-leukemia Jurkat cells by increased concentration of reactive oxygen species and activation of caspase-8 and caspase-9. Journal of Natural Medicines. 65: 488-99
Updegrove TB, Correia JJ, Chen Y, et al. (2011) The stoichiometry of the Escherichia coli Hfq protein bound to RNA. Rna (New York, N.Y.). 17: 489-500
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