Mariam L. Sharaf, Ph.D.

Affiliations: 
2011 Chemistry Duke University, Durham, NC 
Area:
Boronated Nucleic Acids
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Barbara Ramsay Shaw grad student 2011 Duke
 (Exploring the Immunogenicity and Therapeutic Applications of Boranophosphate-modified RNA: siRNA and RNA Aptamers.)
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Publications

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Cheek MA, Sharaf ML, Dobrikov MI, et al. (2013) Inhibition of hepatitis C viral RNA-dependent RNA polymerase by α-P-boranophosphate nucleotides: exploring a potential strategy for mechanism-based HCV drug design. Antiviral Research. 98: 144-52
Ray P, Cheek MA, Sharaf ML, et al. (2012) Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. Nucleic Acid Therapeutics. 22: 295-305
Shaw BR, Moussa L, Sharaf M, et al. (2008) Boranophosphate siRNA-aptamer chimeras for tumor-specific downregulation of cancer receptors and modulators. Nucleic Acids Symposium Series (2004). 655-6
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