Brian M. Gulledge, Ph.D.

Affiliations: 
2003 University of California, Irvine, Irvine, CA 
Area:
Organic Synthesis, Chemical Biology
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A. Richard Chamberlin grad student 2003 UC Irvine
 (Linearized and simplified microcystins as inhibitors of the protein phosphatases 1 and 2A, and subsequent attempts at improving upon the enzymatic selectivity and potency, with an application to map the localization of the enzymes in vivo.)
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Publications

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Alexander MD, Burkart MD, Leonard MS, et al. (2006) A central strategy for converting natural products into fluorescent probes. Chembiochem : a European Journal of Chemical Biology. 7: 409-16
Sandler JS, Fenical W, Gulledge BM, et al. (2005) Fluorescent profiling of natural product producers. Journal of the American Chemical Society. 127: 9320-1
Gulledge BM, Aggen JB, Chamberlin AR. (2003) Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A. Bioorganic & Medicinal Chemistry Letters. 13: 2903-6
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