David J. Montefusco, Ph.D.

Affiliations: 
2007 Chemistry University of Massachusetts, Amherst, Amherst, MA 
Area:
Transmembrane Signaling, Physical Chemistry of Cell Membranes and Protein-Protein Interactions
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"David Montefusco"
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Robert M. Weis grad student 2007 U Mass Amherst
 (Investigations of cluster-mediated adaptive signaling by proteins of the chemotaxis pathways using template directed assembly.)
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Publications

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Montefusco DJ, Matmati N, Hannun YA. (2014) The yeast sphingolipid signaling landscape. Chemistry and Physics of Lipids. 177: 26-40
Montefusco DJ, Chen L, Matmati N, et al. (2013) Distinct signaling roles of ceramide species in yeast revealed through systematic perturbation and systems biology analyses. Science Signaling. 6: rs14
Montefusco DJ, Newcomb B, Gandy JL, et al. (2012) Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. The Journal of Biological Chemistry. 287: 9280-9
Wu BX, Clarke CJ, Matmati N, et al. (2011) Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference. The Journal of Biological Chemistry. 286: 22362-71
Cowart LA, Shotwell M, Worley ML, et al. (2010) Revealing a signaling role of phytosphingosine-1-phosphate in yeast. Molecular Systems Biology. 6: 349
Matmati N, Kitagaki H, Montefusco D, et al. (2009) Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M Journal of Biological Chemistry. 284: 8241-8246
Besschetnova TY, Montefusco DJ, Asinas AE, et al. (2008) Receptor density balances signal stimulation and attenuation in membrane-assembled complexes of bacterial chemotaxis signaling proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 12289-94
Montefusco DJ, Asinas AE, Weis RM. (2007) Liposome-mediated assembly of receptor signaling complexes. Methods in Enzymology. 423: 267-98
Montefusco DJ, Shrout AL, Besschetnova TY, et al. (2007) Formation and activity of template-assembled receptor signaling complexes. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3280-9
Shrout AL, Montefusco DJ, Weis RM. (2003) Template-directed assembly of receptor signaling complexes. Biochemistry. 42: 13379-85
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