Matthew D. McReynolds, Ph.D.

Affiliations: 
2004 University of Kansas, Lawrence, KS, United States 
Area:
Organic Synthesis
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"Matthew McReynolds"
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Parents

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Paul Ronald Hanson grad student 2004 University of Kansas
 (Ring-closingmetathesis to phosphorus heterocycles: Application to DMP 323 analogues and related studies.)
Justin Du Bois post-doc 2004-2006 Stanford
 (Formal Total Synthesis of (+)-Saxitoxin)
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Publications

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Schnute ME, McReynolds MD, Carroll J, et al. (2017) Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype Distinct Screening Hits. Journal of Medicinal Chemistry
Schnute ME, McReynolds MD, Kasten T, et al. (2012) Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. The Biochemical Journal. 444: 79-88
Fleming JJ, McReynolds MD, Du Bois J. (2007) (+)-Saxitoxin: A first and second generation stereoselective synthesis Journal of the American Chemical Society. 129: 9964-9975
Sieck SR, McReynolds MD, Schroeder CE, et al. (2006) Metathesis studies to cyclic enol phosphonamidates Journal of Organometallic Chemistry. 691: 5307-5311
Whitehead A, McReynolds MD, Moore JD, et al. (2005) Multivalent activation in temporary phosphate tethers: a new tether for small molecule synthesis. Organic Letters. 7: 3375-8
McReynolds MD, Dougherty JM, Hanson PR. (2004) Synthesis of phosphorus and sulfur heterocycles via ring-closing olefin metathesis. Chemical Reviews. 104: 2239-58
McReynolds MD, Sprott KT, Hanson PR. (2002) A concise route to structurally diverse DMP 323 analogues via highly functionalized 1,4-diamines. Organic Letters. 4: 4673-6
Sprott KT, McReynolds MD, Hanson PR. (2002) Ring-closing metathesis strategies to P-heterocycles Phosphorus, Sulfur and Silicon and Related Elements. 177: 1807-1809
Sprott KT, McReynolds MD, Hanson PR. (2001) A temporary phosphorus tether/ring-closing metathesis strategy to functionalized 1,4-diamines. Organic Letters. 3: 3939-42
Sprott KT, McReynolds MD, Hanson PR. (2001) Ring-closing metathesis strategies to amino acid-derived P-heterocycles Synthesis. 612-620
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