John K. Frederiksen, Ph.D.

Affiliations: 
2007 University of Chicago, Chicago, IL 
Area:
chemistry and biochemistryof nucleic acids
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"John Frederiksen"
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Joseph A. Piccirilli grad student 2007 Chicago
 (Binding of metal ions and antibody fragments to folded RNA molecules.)
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Publications

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Li NS, Frederiksen JK, Piccirilli JA. (2012) Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites. The Journal of Organic Chemistry. 77: 9889-92
Frederiksen JK, Li NS, Das R, et al. (2012) Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding. Rna (New York, N.Y.). 18: 1123-41
Li NS, Frederiksen JK, Piccirilli JA. (2011) Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage. Accounts of Chemical Research. 44: 1257-69
Li NS, Frederiksen JK, Koo SC, et al. (2011) A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage. Nucleic Acids Research. 39: e31
Wilson TJ, Li NS, Lu J, et al. (2010) Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme. Proceedings of the National Academy of Sciences of the United States of America. 107: 11751-6
Frederiksen JK, Piccirilli JA. (2009) Separation of RNA phosphorothioate oligonucleotides by HPLC. Methods in Enzymology. 468: 289-309
Frederiksen JK, Piccirilli JA. (2009) Identification of catalytic metal ion ligands in ribozymes. Methods (San Diego, Calif.). 49: 148-66
Ye JD, Tereshko V, Frederiksen JK, et al. (2008) Synthetic antibodies for specific recognition and crystallization of structured RNA. Proceedings of the National Academy of Sciences of the United States of America. 105: 82-7
Dai Q, Frederiksen JK, Anderson VE, et al. (2008) Efficient synthesis of [2'-18O]uridine and its incorporation into oligonucleotides: a new tool for mechanistic study of nucleotidyl transfer reactions by isotope effect analysis. The Journal of Organic Chemistry. 73: 309-11
Bensasson RV, Berberan-Santos MN, Brettreich M, et al. (2001) Triplet state properties of malonic acid C60 derivatives C60 [C(COOR)2] R = H, Et; n = 1-6 Physical Chemistry Chemical Physics. 3: 4679-4683
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