Angela F. McKoy, Ph.D.

Affiliations: 
2011 Princeton University, Princeton, NJ 
Area:
Synthetic Biology and Alzheimer's Disease
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Michael H. Hecht grad student 2011 Princeton
 (Characterization of Novel Inhibitors of Alzheimer's Peptide Aggregation and Implications for Disease Therapeutics.)
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Publications

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McKoy AF, Chen J, Schupbach T, et al. (2014) Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chemical Biology & Drug Design. 84: 505-12
McKoy AF, Chen J, Schupbach T, et al. (2012) A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease. The Journal of Biological Chemistry. 287: 38992-9000
Armstrong AH, Chen J, McKoy AF, et al. (2011) Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide. Biochemistry. 50: 4058-67
McKoy A, Hecht M. (2011) P2-481: A high throughput screen identifies compounds that inhibit Alzheimer's peptide aggregation and reduce toxicity in vitro and in drosophila melanogaster Alzheimer's & Dementia. 7: S466-S466
McKoy AF, Hecht M. (2010) P3-270: A high throughput screen identifies compounds that inhibit Abeta peptide aggregation and reduce Abeta toxicity in vitro and in drosophila melanogaster Alzheimer's & Dementia. 6: S531-S531
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