Graham M. West, Ph.D.
Affiliations: | 2009 | Chemistry | Duke University, Durham, NC |
Area:
protein folding and stabilityGoogle:
"Graham West"Mean distance: 9.19 | S | N | B | C | P |
Parents
Sign in to add mentor| Michael C. Fitzgerald | grad student | 2009 | Duke | |
| (A covalent modification technique for protein-ligand binding analysis using mass spectrometry-based proteomics platforms.) | ||||
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Publications
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| Tallon AM, Xu Y, West GM, et al. (2023) Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be "Switched Off" Bioorthogonal Chemistry Inside Live Cells. Journal of the American Chemical Society |
| Xu Y, West GM, Abdelmessih M, et al. (2021) A Comparison of Two Stability Proteomics Methods for Drug Target Identification in OnePot 2D Format. Acs Chemical Biology |
| Hesp KD, Xiao J, West GM. (2020) Late-stage synthesis and application of photoreactive probes derived from direct benzoylation of heteroaromatic C-H bonds. Organic & Biomolecular Chemistry |
| Bandyopadhyay A, Van Eps N, Eger BT, et al. (2018) A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin. Journal of Molecular Biology |
| Zorba A, Nguyen C, Xu Y, et al. (2018) Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proceedings of the National Academy of Sciences of the United States of America |
| Byrnes LJ, Xu Y, Qiu X, et al. (2018) Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange. Scientific Reports. 8: 4664 |
| Kurumbail RG, West GM, Dharmarajan V, et al. (2018) Biophysical Interactions of Direct AMPK Activators. Methods in Molecular Biology (Clifton, N.J.). 1732: 29-55 |
| Nguyen C, West GM, Geoghegan KF. (2017) Emerging Methods in Chemoproteomics with Relevance to Drug Discovery. Methods in Molecular Biology (Clifton, N.J.). 1513: 11-22 |
| Zuhl AM, Nolan CE, Brodney MA, et al. (2016) Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature Communications. 7: 13042 |
| Li J, Xu H, West GM, et al. (2016) Label-free technologies for target identification and validation Medchemcomm. 7: 769-777 |