Graham M. West, Ph.D.

2009 Chemistry Duke University, Durham, NC 
protein folding and stability
"Graham West"
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Michael C. Fitzgerald grad student 2009 Duke
 (A covalent modification technique for protein-ligand binding analysis using mass spectrometry-based proteomics platforms.)
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Zorba A, Nguyen C, Xu Y, et al. (2018) Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proceedings of the National Academy of Sciences of the United States of America
Byrnes LJ, Xu Y, Qiu X, et al. (2018) Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange. Scientific Reports. 8: 4664
Zuhl AM, Nolan CE, Brodney MA, et al. (2016) Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature Communications. 7: 13042
Mari Y, West GM, Scharager-Tapia C, et al. (2015) SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex. Journal of Proteome Research. 14: 4571-80
Pascal BD, West GM, Scharager-Tapia C, et al. (2015) Software Analysis of Uncorrelated MS1 Peaks for Discovery of Post-Translational Modifications. Journal of the American Society For Mass Spectrometry
Yang L, Yang D, de Graaf C, et al. (2015) Conformational states of the full-length glucagon receptor. Nature Communications. 6: 7859
Kang Y, Zhou XE, Gao X, et al. (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature
Adhikari J, West GM, Fitzgerald MC. (2015) Global analysis of protein folding thermodynamics for disease state characterization. Journal of Proteome Research. 14: 2287-97
Corzo CA, Mari Y, Chang MR, et al. (2015) Antiproliferation activity of a small molecule repressor of liver receptor homolog 1. Molecular Pharmacology. 87: 296-304
West GM, Willard FS, Sloop KW, et al. (2014) Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain. Plos One. 9: e105683
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