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Yang Wei, Ph.D.

Affiliations: 
2013 GSAS - Chemistry Boston College, Newton, MA, United States 
Area:
31P for phospholipase assays and substrate characterization, indirect detection of 13C or 15N uptake and turnover in archaea and some mammalian cells
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"Yang Wei"
Mean distance: 9.18
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Mary Fedarko Roberts grad student 2013 Boston College
 (Mechanistic studies of two phosphatase enzymes involved in inostiol metabolism.)

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Publications

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Wei Y, Stec B, Redfield AG, et al. (2015) Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation. The Journal of Biological Chemistry. 290: 1592-606
Wei Y, Roberts MF. (2012) Probing the Activator and Hydrophobic Substrate Binding Sites of PTEN by 31P NMR Biophysical Journal. 102: 494a
Wei Y, Roberts MF. (2011) 31P NMR Studies of Active Site and Activator Site Ligands Binding to PTEN Biophysical Journal. 100: 552a
Wang Q, Wei Y, Mottamal M, et al. (2010) Understanding the stereospecific interactions of 3-deoxyphosphatidylinositol derivatives with the PTEN phosphatase domain. Journal of Molecular Graphics & Modelling. 29: 102-14
Li Z, Stieglitz KA, Shrout AL, et al. (2010) Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition. Protein Science : a Publication of the Protein Society. 19: 309-18
Longo CM, Wei Y, Roberts MF, et al. (2009) Asymmetric Syntheses of L,L- and L,D-di-myo-inositol-1,1'-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures. Angewandte Chemie (International Ed. in English). 48: 4158-61
Wei Y, Wang YK, Xu Y, et al. (2009) PTEN Inhibition Study by Synthetic 3-Deoxy-PI Derivatives Biophysical Journal. 96: 441a
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