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Ian J. Griswold, Ph.D.

Affiliations: 
2001 University of Oregon, Eugene, OR, United States 
Area:
protein structure and function, nuclear magnetic resonance
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"Ian Griswold"
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Frederick W. Dahlquist grad student 2001 University of Oregon
 (The structural role of CheW in the bacterial chemotaxis receptor complex.)

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Seo JH, Wood LJ, Agarwal A, et al. (2010) A specific need for CRKL in p210BCR-ABL-induced transformation of mouse hematopoietic progenitors. Cancer Research. 70: 7325-35
Johnson KJ, Griswold IJ, O'Hare T, et al. (2009) A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice. Plos One. 4: e7439
Griswold IJ, MacPartlin M, Bumm T, et al. (2006) Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib Molecular and Cellular Biology. 26: 6082-6093
Corbin AS, Demehri S, Griswold IJ, et al. (2005) In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit. Blood. 106: 227-34
Corbin AS, Griswold IJ, La Rosée P, et al. (2004) Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970. Blood. 104: 3754-7
Griswold IJ, Shen LJ, La Rosée P, et al. (2004) Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood. 104: 2912-8
Corbin AS, Demehri S, Griswold IJ, et al. (2004) In Vitro and In Vivo Activity of the Src/Abl Kinase Inhibitor AP23464 and Analogs Against Activation Loop Mutants of KIT. Blood. 104: 793-793
Griswold IJ, Bumm T, O’Hare T, et al. (2004) Investigation of the Biological Differences between Bcr-Abl Kinase Mutations Resistant to Imatinib. Blood. 104: 555-555
Griswold IJ, Dahlquist FW. (2002) The dynamic behavior of CheW from Thermotoga maritima in solution, as determined by nuclear magnetic resonance: implications for potential protein-protein interaction sites. Biophysical Chemistry. 101: 359-73
Griswold IJ, Dahlquist FW. (2002) Bigger is better: megadalton protein NMR in solution. Nature Structural Biology. 9: 567-8
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