Charles A. DiTusa, Ph.D.

Affiliations: 
2000 Duke University, Durham, NC 
Area:
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
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"Charles DiTusa"
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Eric J. Toone grad student 2000 Duke
 (Part 1: Asymmetric hydroboration of enamines, enamides and aryl olefins catalyzed with rhodium complexes of DuPHOS, BPE and novel phospholanes. Part : Thermodynamics of metal binding to apo-carbonic anhydrase.)
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Publications

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DiTusa C, Kozar MP, Pybus B, et al. (2014) Causal prophylactic efficacy of primaquine, tafenoquine, and atovaquone-proguanil against Plasmodium cynomolgi in a rhesus monkey model. The Journal of Parasitology. 100: 671-3
Edstein MD, Kotecka BM, Ager AL, et al. (2007) Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model. The Journal of Antimicrobial Chemotherapy. 60: 811-8
Gutteridge CE, Nichols DA, Curtis SM, et al. (2006) In vitro and in vivo efficacy and in vitro metabolism of 1-phenyl-3-aryl-2-propen-1-ones against Plasmodium falciparum. Bioorganic & Medicinal Chemistry Letters. 16: 5682-6
Guan J, Zhang Q, Montip G, et al. (2005) Structure identification and prophylactic antimalarial efficacy of 2-guanidinoimidazolidinedione derivatives. Bioorganic & Medicinal Chemistry. 13: 699-704
Tang Y, Dong Y, Karle JM, et al. (2004) Synthesis of tetrasubstituted ozonides by the Griesbaum coozonolysis reaction: diastereoselectivity and functional group transformations by post-ozonolysis reactions. The Journal of Organic Chemistry. 69: 6470-3
DiTusa CA, McCall KA, Christensen T, et al. (2001) Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants. Biochemistry. 40: 5345-51
DiTusa CA, Christensen T, McCall KA, et al. (2001) Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase. Biochemistry. 40: 5338-44
Kim HJ, Choi YM, Yang APP, et al. (1996) Microbiological and chemical investigation of ohmic heating of particulate foods using A 5 kW ohmic system Journal of Food Processing and Preservation. 20: 41-58
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