David M. Gooden, Ph.D.

2006 Duke University, Durham, NC 
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
"David Gooden"
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Eric J. Toone grad student 2006 Duke
 (Synthesis and physical organic chemistry of C-nitroso compounds: A study of C-nitroso ketones as selective nitrosonium donors.)
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Kanju P, Chen Y, Lee W, et al. (2016) Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Scientific Reports. 6: 26894
Chitneni SK, Reitman ZJ, Gooden DM, et al. (2016) Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs. European Journal of Medicinal Chemistry. 119: 218-230
Su G, Letcher RJ, Yu H, et al. (2016) Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure. Chemosphere. 149: 314-319
Su G, Letcher RJ, Crump D, et al. (2015) In vitro metabolism of the flame retardant triphenyl phosphate in chicken embryonic hepatocytes and the importance of the hydroxylation pathway Environmental Science and Technology Letters. 2: 100-104
Claytor K, Theis T, Feng Y, et al. (2014) Accessing long-lived disconnected spin-1/2 eigenstates through spins > 1/2. Journal of the American Chemical Society. 136: 15118-21
Reitman ZJ, Duncan CG, Poteet E, et al. (2014) Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia. The Journal of Biological Chemistry. 289: 23318-28
Xia W, Gooden D, Liu L, et al. (2014) Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis. Plos One. 9: e88983
Iwabuchi M, Sheng H, Thompson JW, et al. (2014) Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 425-32
Sinclair SM, Bhattacharyya J, McDaniel JR, et al. (2013) A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 171: 38-47
Fang M, Webster TF, Gooden D, et al. (2013) Investigating a novel flame retardant known as V6: measurements in baby products, house dust, and car dust. Environmental Science & Technology. 47: 4449-54
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