David A. Carlson, Ph.D.

Affiliations: 
2010 Chemistry Duke University, Durham, NC 
Area:
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
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"David Carlson"
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Parents

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Eric J. Toone grad student 2010 Duke
 (New approaches to studying non-covalent molecular interactions in nano-confined environments.)
Timothy Arthur James Haystead post-doc 2010- Duke
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Publications

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Alwarawrah Y, Hughes P, Loiselle D, et al. (2016) Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chemical Biology
MacDonald JA, Sutherland C, Carlson DA, et al. (2015) A Small Molecule Pyrazolo[3,4-d]pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle. Molecular Pharmacology
Howe MK, Bodoor K, Carlson DA, et al. (2014) Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70. Chemistry & Biology. 21: 1648-59
Carlson DA, Franke AS, Weitzel DH, et al. (2013) Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. Acs Chemical Biology. 8: 2715-23
Bowers CM, Carlson DA, Rivera M, et al. (2013) Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy. The Journal of Physical Chemistry. B. 117: 4755-62
Bowers CM, Carlson DA, Shestopalov AA, et al. (2012) A general and efficient cantilever functionalization technique for AFM molecular recognition studies. Biopolymers. 97: 761-5
Hughes PF, Barrott JJ, Carlson DA, et al. (2012) A highly selective Hsp90 affinity chromatography resin with a cleavable linker. Bioorganic & Medicinal Chemistry. 20: 3298-305
Haines NR, VanZanten AN, Cuneo AA, et al. (2011) A sulfone-based strategy for the preparation of 2,4-disubstituted furan derivatives. The Journal of Organic Chemistry. 76: 8131-7
Rivera M, Morris C, Carlson D, et al. (2010) Minimizing tip-sample contact force in automated atomic force microscope based force spectroscopy Proceedings of the Asme International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, Detc2009. 6: 731-736
VanZanten A, Mullaugh K, Harrington R, et al. (2004) Improved synthesis of 2,3-dibromo-1-(phenylsulfonyl)-1-propene (DBP) Synthesis. 2611-2613
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