Todd Mollan, Ph.D.
Affiliations: | 2011 | Rice University, Houston, TX |
Area:
myoglobin, hemoglobinGoogle:
"Todd Mollan"Mean distance: 10.58 | S | N | B | C | P |
Parents
Sign in to add mentor| John S. Olson | grad student | 2011 | Rice University | |
| (The Role of Alpha-Hemoglobin Stabilizing Protein in Human Hemoglobin Assembly.) | ||||
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Publications
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| Strader MB, Hicks WA, Kassa T, et al. (2014) Post-translational transformation of methionine to aspartate is catalyzed by heme iron and driven by peroxide: a novel subunit-specific mechanism in hemoglobin. The Journal of Biological Chemistry. 289: 22342-57 |
| Mollan TL, Jia Y, Banerjee S, et al. (2014) Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin. Free Radical Biology & Medicine. 69: 265-77 |
| Soman J, Strader M, Hicks W, et al. (2014) Crystallographic evidence for oxidative Met→Asp conversion in human hemoglobin Acta Crystallographica Section a Foundations and Advances. 70: C310-C310 |
| Dickson CF, Rich AM, D'Avigdor WM, et al. (2013) α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond. The Journal of Biological Chemistry. 288: 19986-20001 |
| Mollan TL, Alayash AI. (2013) Redox reactions of hemoglobin: mechanisms of toxicity and control. Antioxidants & Redox Signaling. 18: 2251-3 |
| Mollan TL, Banerjee S, Wu G, et al. (2013) α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide. The Journal of Biological Chemistry. 288: 4288-98 |
| Varnado CL, Mollan TL, Birukou I, et al. (2013) Development of recombinant hemoglobin-based oxygen carriers. Antioxidants & Redox Signaling. 18: 2314-28 |
| Mollan TL, Abraham B, Strader MB, et al. (2012) Familial secondary erythrocytosis due to increased oxygen affinity is caused by destabilization of the T state of hemoglobin Brigham (α₂β₂(Pro100Leu)). Protein Science : a Publication of the Protein Society. 21: 1444-55 |
| Mollan TL, Khandros E, Weiss MJ, et al. (2012) Kinetics of α-globin binding to α-hemoglobin stabilizing protein (AHSP) indicate preferential stabilization of hemichrome folding intermediate. The Journal of Biological Chemistry. 287: 11338-50 |
| Khandros E, Mollan TL, Yu X, et al. (2012) Insights into hemoglobin assembly through in vivo mutagenesis of α-hemoglobin stabilizing protein. The Journal of Biological Chemistry. 287: 11325-37 |