George P. Lisi, Ph.D.

Affiliations: 
2014 Chemistry Dartmouth College, Hanover, NH, United States 
Area:
Biophysical chemistry, protein dynamics, cell signaling, laser spectroscopy, NMR
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"George Lisi"
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John R. Miecznikowski grad student 2008-2009 Fairfield University
Ekaterina V. Pletneva grad student 2014 Dartmouth
 (Thermodynamic and Spectroscopic Studies of Metalloprotein Stability, Ligation, and Reactivity.)
J. Patrick Loria post-doc Yale
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Publications

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Skeens E, East KW, Lisi GP. (2020) H, C,  N backbone resonance assignment of the recognition lobe subdomain 3 (Rec3) from Streptococcus pyogenes CRISPR-Cas9. Biomolecular Nmr Assignments
Pantouris G, Khurana L, Ma A, et al. (2020) Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chemical Biology
East KW, Newton JC, Morzan UN, et al. (2019) Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics. Journal of the American Chemical Society
East KW, Skeens E, Cui JY, et al. (2019) NMR and computational methods for molecular resolution of allosteric pathways in enzyme complexes. Biophysical Reviews
Belato HB, East KW, Lisi GP. (2019) H, C, N backbone and side chain resonance assignment of the HNH nuclease from Streptococcus pyogenes CRISPR-Cas9. Biomolecular Nmr Assignments
Negre CFA, Morzan UN, Hendrickson HP, et al. (2018) Eigenvector centrality for characterization of protein allosteric pathways. Proceedings of the National Academy of Sciences of the United States of America
Amacher JF, Zhong F, Lisi GP, et al. (2018) Correction to "A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch". Journal of the American Chemical Society
Lisi GP, Currier AA, Loria JP. (2018) Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation. Frontiers in Molecular Biosciences. 5: 4
Lisi GP, Loria JP. (2017) Allostery in enzyme catalysis. Current Opinion in Structural Biology. 47: 123-130
Lisi GP, East KW, Batista VS, et al. (2017) Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity. Proceedings of the National Academy of Sciences of the United States of America
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