Michael E. Danielson, Ph.D.

Affiliations: 
2003 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Organic Chemistry
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"Michael Danielson"
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SNBCP

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Thomas Robert Hoye grad student 2003 UMN
 (A total synthesis of callipeltoside A.)
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Michel KS, Fulton RB, Leonardo SM, et al. (2017) Abstract 1703: A novel tumor vaccine platform: direct conjugation of antigens to the β glucan PAMP Imprime PGG enhances antigen presentation and T cell priming Cancer Research. 77: 1703-1703
Chan AS, Jonas AB, Qiu X, et al. (2016) Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation. Plos One. 11: e0165909
Fulton RB, Leonardo SM, Michel KS, et al. (2016) Abstract B019: Imprime PGG, a soluble β-glucan, binds to and activates dendritic cells resulting in enhanced T cell priming, expansion, and cytokine production Cancer Immunology Research. 4
Fulton RB, Leonardo SM, Jonas AB, et al. (2016) Abstract LB-089: Imprime PGG, a β-glucan PAMP (pathogen-associated molecular pattern), effectively elicits in vivo maturation of antigen presenting cells in mice and humans, suggesting potential synergy with checkpoint inhibitor therapy Cancer Research. 76
Fulton RB, Chan AS, Leonardo SM, et al. (2015) Abstract A99: Imprime PGG, a soluble yeast β-glucan, induces dendritic cell maturation, upregulating co-stimulatory and activation markers to enhance antigen presentation and T cell priming Molecular Cancer Therapeutics. 14
Yokoyama Y, Nelson MI, Ottoson NC, et al. (2013) Abstract B65: Immune cell priming and potentiation of anti-tumor effects by Imprime PGG® Cancer Research. 73
Hoye TR, Danielson ME, May AE, et al. (2010) Total synthesis of (-)-callipeltoside A. The Journal of Organic Chemistry. 75: 7052-60
Hoye TR, Danielson ME, May AE, et al. (2008) Dual macrolactonization/pyran-hemiketal formation via acylketenes: applications to the synthesis of (-)-callipeltoside A and a lyngbyaloside B model system. Angewandte Chemie (International Ed. in English). 47: 9743-6
Hoye RC, Baigorria AS, Danielson ME, et al. (1999) Synthesis of elenic acid, an inhibitor of topoisomerase II Journal of Organic Chemistry. 64: 2450-2453
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